Structural changes of smooth muscle in congenital ureteropelvic junction obstruction


Hosgor M., Karaca I., Ulukus C., Ozer E., Ozkara E., Sam B., ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.40, sa.10, ss.1632-1636, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 10
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.jpedsurg.2005.06.025
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1632-1636
  • Anahtar Kelimeler: myosin heavy chains, smooth muscle, ureteropelvic junction obstruction, HEAVY-CHAIN ISOFORMS, MESENCHYMAL-EPITHELIAL INTERACTIONS, RENAL PELVIS, EXPRESSION, BLADDER, HYDRONEPHROSIS, INNERVATION, URETER, TISSUE
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Hayır

Özet

Background/Purpose: Ureteropelvic junction (UPJ) obstruction is the most common cause of congenital hydronephrosis. Previous studies have reported that the excess amount of collagen restricting mobility and resiliency of the UPJ is the result of an impaired collagen production by anomalous smooth muscle cells (SMCs). Our purpose was to evaluate the role of SMC differentiation in the pathogenesis of UPJ obstruction.