Prevalence of MEFV gene mutations in a large cohort of patients with suspected familial Mediterranean fever in Central Anatolia

YILDIRIM M. E., KÜÇÜK KURTULGAN H., ÖZDEMİR Ö., KILIÇGÜN H., Aydemir D. S., Baser B., ...Daha Fazla

ANNALS OF SAUDI MEDICINE, cilt.39, sa.6, ss.382-387, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 6
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5144/0256-4947.2019.382
  • Dergi Adı: ANNALS OF SAUDI MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.382-387
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

BACKGROUND: Familial Mediterranean fever (FMF), an autosomal recessive, autoinflammatory disease that is common in Arabs, Jews, Armenians and Turks, is caused by mutations in the MEFV gene, which encodes a protein called pyrin. The disease is characterised by recurrent fever, peritonitis, pleuritis, abdominal pain and arthralgia.