Linezolid alone and in combination with rifampicin prevents experimental vascular graft infection due to methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis

Sacar, MUSTAFA; Sacar, SUZAN; Kaleli, Ilknur; Önem, Gokhan; Turgut, Huseyin; Gökşin, Ibrahim; Özcan, Vefa; İnan, Bilal; Duver, Harun; Baltalarlı, Ahmet

doi:10.1016/j.jss.2006.10.003

Linezolid alone and in combination with rifampicin prevents experimental vascular graft infection due to methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis

Sacar M., Sacar S., Kaleli I., Önem G., Turgut H., Gökşin I., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.139, sa.2, ss.170-175, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 139 Sayı: 2
Basım Tarihi: 2007
Doi Numarası: 10.1016/j.jss.2006.10.003
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.170-175
Çanakkale Onsekiz Mart Üniversitesi Adresli: Hayır

Özet

Background. In this report we describe the in vivo antibacterial activity of linezolid in an experimental graft infection model in rats and compare it with teicoplanin. The objective of this study was also to determine the effects of the interaction of linezolid when it was combined with rifampicin and test this effect against strains of methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.