Protective effect of decorin on acute ischaemia-reperfusion injury in the rat kidney

ALAN C., Kocoglu H., Altintas R., Alici B., ERSAY A. R.

ARCHIVES OF MEDICAL SCIENCE, cilt.7, sa.2, ss.211-216, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5114/aoms.2011.22069
  • Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.211-216
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Introduction: Transforming growth factor-beta 1 (TGF-beta 1) has a crucial role in collagen synthesis and fibrosis. TGF-beta 1 can be antagonized and/or reduced by the action of certain agents. We propose to identify the role of decorin in treatment of tubular and interstitial fibrosis and in the inhibition of TGF-beta 1 in an acute ischaemic kidney.