Applications of graphene in electrochemical sensing and biosensing

Bahadir E. B., SEZGİNTÜRK M. K.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, vol.76, pp.1-14, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 76
  • Publication Date: 2016
  • Doi Number: 10.1016/j.trac.2015.07.008
  • Journal Name: TRAC-TRENDS IN ANALYTICAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1-14
  • Keywords: Graphene, Electrochemical sensors, Electrochemical biosensors, Graphene oxide, Graphite oxide, GLASSY-CARBON ELECTRODE, OXIDASE DECORATED GRAPHENE, HIGH-SENSITIVE DETECTION, LABEL-FREE DETECTION, GLUCOSE-OXIDASE, HYDROGEN-PEROXIDE, FUNCTIONALIZED GRAPHENE, COMPOSITE FILM, NANOPARTICLES NANOCOMPOSITE, CANCER BIOMARKER
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Graphene (GR), the thinnest and the lightest sp(2) carbon nanomaterial, has exhibited extraordinary properties in terms of fast electron mobility, high current density, high mechanical strength, excellent thermal conductivity, and ultra-larger surface area. These characteristics make GR an ideal nanomaterial for nanoelectronics, nanodevices, and nanocomposites. GR-based biosensors, thus, have attracted great attention toward providing a novel sensor platform for analyzing the target biomolecules with high sensitivity and selectivity. Moreover, GR has been used in chemical sensors because of its excellent electrochemical properties. Using GR and GR derivative-modified electrodes, enzyme and DNA biosensors, immunosensors, and chemical sensors have been developed. In this review, the methods of immobilization involved in developing biosensors and chemical sensors have been summarized in Tables. Moreover, the linear ranges, limits of detection (LODs), reproducibilities, and reusabilities of these reported biosensors and chemical sensors are compared in detail. Future prospects in this rapidly developing field are also discussed.