Carbon dioxide pneumoperitoneum induces systemic oxidative stress: a clinical study


ARAN T., Unsal M. A. , GÜVEN S., KART C., Cetin E. C. , ALVER A.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol.161, no.1, pp.80-83, 2012 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 161 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1016/j.ejogrb.2011.11.027
  • Journal Name: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.80-83
  • Keywords: Biochemical marker, Ischemia-modified albumin, Laparoscopy, Safety, INCREASED INTRAABDOMINAL PRESSURE, ALBUMIN COBALT BINDING, MYOCARDIAL-ISCHEMIA, LAPAROSCOPIC CHOLECYSTECTOMY, BLOOD-FLOW, ANTIOXIDANT, SURGERY, MORPHOLOGY, ASSAY, CONTRACTILITY

Abstract

Objective: To investigate the effect of carbon dioxide pneumoperitoneum on systemic oxidative stress by using serum oxidative stress markers (ischemia modified albumin (IMA), malondialdehyde (MDA), total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI)) and to compare their effectiveness at clinically accepted safe intra-abdominal pressure levels (<12 mmHg).