(E)-2-[(2-Chlorobenzylimino)methyl]methoxyphenol has been synthesized from the reaction of 2-hydroxy-3-methoxy-1-benzaldehyde(o-vanillin) with 2-chlorobenzylamine. The title compound has been characterized by using elemental analysis, FT-IR, H-1 NMR, C-13 NMR and UV-vis spectroscopic techniques. The crystal structure of the title compound has also been examined cyrstallographically. It crystallizes in the orthorhombic space group Pbca with unit cell parameters: a = 7.208(1)angstrom, b = 13.726(2)angstrom, c= 27.858(4) angstrom, V= 2756.0(1) angstrom(3), D, = 1.18 g cm(-3) and Z= 8. The crystal structure was solved by direct methods and refined by full-matrix least squares to a find R=0.046 for 2773 observed reflections. (C) 2009 Elsevier B.V. All rights reserved.