Ethanolic extract of Bjekandera adusta (Wind.) P. Karst. was investigated for its antiyeast activity against Hanseniaspora guilliermondii, Rhodotorula rubra, Kluyveromyces fragilis, Kluyveromyces marxianus, Debaryomyces hansenii,Candida albicans. Candida glabrata, Candida utilis and Cryptococcus neoformans by disc diffusion method. The extracts. had strong effects against Candida albicans and Cryptococcus neoformans, but weak activity was seen against the other yeast cultures used in present study.