Flow-Injection Amperometric Determination of Glucose Using Nickel Oxide-Cobalt (II,III) Oxide and Nickel Oxide-Copper Nanoparticle Modified Pencil Graphite Electrodes

AYAZ S., KARAKAYA S., EMİR G., Usakligil N., GİRAY DİLGİN D., DİLGİN Y.

ANALYTICAL LETTERS, vol.55, no.13, pp.2046-2057, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 13
  • Publication Date: 2022
  • Doi Number: 10.1080/00032719.2022.2043890
  • Journal Name: ANALYTICAL LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Food Science & Technology Abstracts, Metadex, Veterinary Science Database, Civil Engineering Abstracts
  • Page Numbers: pp.2046-2057
  • Keywords: Amperometry, pencil graphite electrode, flow injection analysis, cyclic voltammetry, electrochemical impedance spectroscopy, glucose, SENSOR
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

This study features an enzyme-free amperometric determination of glucose with flow injection analysis (FIA) using pencil graphite electrodes (PGEs) modified with nickel oxide-cobalt (II,III) oxide (NiO-Co3O4/PGE) and nickel oxide-copper nanoparticle (NiO-CuNPs/PGE). Both modified PGEs exhibited excellent electrocatalytic activity toward oxidation of glucose in strong alkaline media since they enhanced the peak current compared with the bare PGE and single metal oxide- or metal nanoparticle-modified PGEs. Flow-injection (FI) amperometry showed the linear response range, the limit of detection and sensitivity for NiO-Co3O4/PGE and NiO-CuNPs/PGE were 1.0-1000 mu M, 0.23 mu M and 586 mu A mM(-1) cm(-2), and 0.10-250 mu M, 0.03 mu M and 949 mu A mM(-1) cm(-2), respectively. Glucose was determined in real samples with good accuracy and precision.