Does the maxillary sinus have a triggering role in nasal nitric oxide synthesis?

GÜÇLÜ O. , ULUDAĞ A. , AKÇALI A. , Tekin K. , ERDOĞAN H. , SILAN F. , ...More

RHINOLOGY, vol.50, no.4, pp.402-407, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.4193/rhin12.081
  • Title of Journal : RHINOLOGY
  • Page Numbers: pp.402-407


Objectives: We investigated whether the maxillary sinus plays a stimulatory role in nasal nitric oxide (NO) synthesis. Research on sinusitis and nasal polyps has found low NO levels in exhaled air and linked this to obstruction of the ostium. However, the major source of NO in exhaled air is thought to be the nasal mucosa. In this study, Streptococcus pneumoniae was applied to the maxillary sinus to investigate changes in NO synthesis of the nasal mucosa.