Presence of Peripheral Neuropathy Does Not Affect Urine 6-Sulfatoxymelatonin Levels in Type 2 Diabetics


KURT K. , KARAKILIÇ E. , OCAK Ö. , Cakin S.

NEUROENDOCRINOLOGY LETTERS, vol.42, no.1, pp.33-42, 2021 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 1
  • Publication Date: 2021
  • Title of Journal : NEUROENDOCRINOLOGY LETTERS
  • Page Numbers: pp.33-42

Abstract

BACKGROUND: Oxidative stress plays a crucial role in the pathogenesis of diabetic peripheral neuropathy. Melatonin is one of the most powerful antioxidant substances and its role in the pathogenesis of diabetes has been the focus of much research. However, no data exist on melatonin levels in diabetic peripheral neuropathy. We investigated how levels of urinary 6-sulfatoxymelatonin, the main metabolite of melatonin, differed in diabetic peripheral neuropathy.