© 2019, Duzce University Medical School. All rights reserved.Peritonitis in patients receiving continuous ambulatory peritoneal dialysis (CAPD) is one of the most important causes of increased hospital and antibiotic costs, and mortality and morbidity in these patients. Although the majority of peritonitis cases are caused by Gram positive bacteria, sometimes unexpected microorganism can cause peritonitis. Chryseobacterium indologenes is a member of the human flora widely found in nature and rarely causes of human infections. In this case report, it is aimed to present 68 year-old male patient with peritonitis due to Chryseobacterium indologenes who has been receiving CAPD for two years. The patient responded well to intravenous plus intraperitoneal ciprofloxacin therapy. There was no need to remove the peritoneal dialysis catheter, in this case. Chryseobacterium indologenesis is an extremely rare cause of peritonitis associated with CAPD. This microorganism-induced peritonitis can be treated successfully with intravenous plus intraperitoneal antibiotics without need for withdrawal of the peritoneal catheter.