Research Information System
International Journal for Multidisciplinary Research, vol.6, no.4, pp.1-11, 2024 (Peer-Reviewed Journal)
Throughout their lives, all organisms are affected by environmental factors. The duration of the
photoperiod and the type of diet to which the organism is exposed are among the most important
parameters of the interaction between genes and the environment. In this study, Syrian hamsters were left
in two separate light conditions, 16L (04.00-20.00) and 8L (12.00-20.00). Adult hamsters were
randomized into two major groups and fed with ad-libitum and methyl-rich diets. Daily feed intake and
weekly body weights were monitored. At the end of 8 weeks, the hypothalamus tissues of Syrian hamsters
were isolated by decapitating them at four different times of the day. lights on, mid-day, lights off, and
midnight. As shown in the results of DNA materials by the Trisole method, global methylation amounts
were measured by ELISA. Hamsters fed a diet high in methyl consumed more nutrients than those supplied
ad-libitum. (p<0,05). There was no effect of diet type on body weight, The amount of methylation
increased in both long and short photoperiods during the hours when the lights were off (p<0,05).
Although each content of methyl-rich foods affects different enzymes or hormones, it has an important
role in metabolic activities. Photoperiodically varying methylation balances were also shown to vary
widely in multiple ways depending on the methyl level in the environment.