Akademik Veri Yönetim Sistemi
3rd International Health Services Congress, Mersin, Türkiye, 3 - 04 Şubat 2026, cilt.1, sa.1, ss.160-161, (Özet Bildiri)
Acinetobacter baumannii is a Gram-negative bacterium that causes hospital-acquired infectious disease in intensive care units. Furthermore, it poses a significant public health problem and makes treatment increasingly difficult because it can develop multidrug resistance to antibiotics. Therefore, research continues to provide new and alternative treatment methods that may be effective. Plant oils, on the other hand, have been used historically in mummification, the pharmaceutical industry, and medical fields and are known to exhibit antimicrobial and antioxidant properties due to the bioactive agents they contain, such as terpenes, flavonoids, and phenolic compounds. In this study, the antibacterial activity of 20 different commercial plant fixed and essential oils against the Acinetobacter baumannii isolate was evaluated using the agar well diffusion method. The study determined that bitter almond, chili pepper, bitter apple, anise, juniper, safflower, horse chestnut, avocado, calendula, rosemary, pine turpentine, black cumin, bay leaf seed, rose, coconut, nettle, St. John's wort, and olive oils tested did not possess antibacterial activity. However, black pepper oil showed an inhibition zone diameter of 11.17 ± 0.72 mm, and lavender oil 11.19 ± 0.50 mm. In conclusion, among the selected oils, only black pepper and lavender showed significant inhibition zones against the Acinetobacter baumannii isolate and exhibited antibacterial activity. Antibacterial activity depends on the biologically active components in the plant oil. The chemical composition of the oil is determined by factors such as the plant's harvesting period, storage conditions, and processing methods. Therefore, the finding that none of the 18 oils used in the study possessed antibacterial activity is related to the composition of the oil used. Additionally, because these products are commercially produced, their contents may not be pure or may be diluted for profit. This directly affects antibacterial activity. However, pure vegetable oils and their components are potential natural antimicrobial agents against multidrug-resistant bacteria, such as Acinetobacter baumannii.
Keywords: Essential oil, Fixed oil, Antibacterial activity