Comparison of new and classical point mutations associated with clarithromycin resistance in Helicobacter pylori strains isolated from dyspeptic patients and their effects on phenotypic clarithromycin resistance

KOCAZEYBEK B. S., Sakli M. K., Yuksel P., Demirci M., Caliskan R., Sarp T. Z., ...More

JOURNAL OF MEDICAL MICROBIOLOGY, vol.68, no.4, pp.566-573, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 68 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.1099/jmm.0.000944
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.566-573
  • Keywords: Helicobacter pylori, A2115G, A2144T and G2141A, point mutations, clarithromycin, RIBOSOMAL-RNA GENE, ANTIBIOTIC-RESISTANCE, MACROLIDE RESISTANCE, METRONIDAZOLE, PREVALENCE, ASSAY, RISK
  • Çanakkale Onsekiz Mart University Affiliated: No


Purpose. We aimed to investigate the presence of three recently identified point mutations (A2115G, G2141A and A2144T) of the 23 S rRNA gene and compare them with the three most frequently encountered point mutations (A2142G, A2142C and A2143G) in Helicobacter pylori strains in Turkey.