Temporal analysis of reassortment and molecular evolution of Cucumber mosaic virus: Extra clues from its segmented genome

ohshima K., MATSUMOTO K., yasaka R., NISHIYAMA M., SOEJIMA K., KORKMAZ S., ...Daha Fazla

VIROLOGY, cilt.487, ss.188-197, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 487
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.virol.2015.09.024
  • Dergi Adı: VIROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.188-197
  • Anahtar Kelimeler: Cucumber mosaic virus, Cucumovirus, Evolution, Timescale, Reassortment, Selection, Synonymous sites, PHYLOGENETIC ANALYSES, RECOMBINATION, POPULATIONS, PERFORMANCE, MODELS, DNA
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Cucumber mosaic virus (CMV) is a damaging pathogen of over 200 mono- and dicotyledonous crop species worldwide. It has the broadest known host range of any virus, but the timescale of its evolution is unknown. To investigate the evolutionary history of this virus, we obtained the genomic sequences of 40 CMV isolates from brassicas sampled in Iran, Turkey and japan, and combined them with published sequences. Our synonymous ('silent') site analyses revealed that the present CMV population is the progeny of a single ancestor existing 1550-2600 years ago, but that the population mostly radiated 295-545 years ago. We found that the major CMV lineages are not phylogeographically confined, but that recombination and reassortment is restricted to local populations and that no reassortant lineage is more than 251 years old. Our results highlight the different evolutionary patterns seen among viral pathogens of brassica crops across the world. (C) 2015 Elsevier Inc. All rights reserved.