DOUBLE TRANSLOCATION: AN INTERESTING FAMILY HISTORY
BALKAN JOURNAL OF MEDICAL GENETICS, cilt.16, sa.1, ss.77-80, 2013 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 16 Sayı: 1
- Basım Tarihi: 2013
- Doi Numarası: 10.2478/bjmg-2013-0022
- Dergi Adı: BALKAN JOURNAL OF MEDICAL GENETICS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.77-80
- Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet
Özet
Double balanced translocations are particularly rare and the risk of a fetus with an unbalanced chromosomal anomaly is greater than for single translocation carriers. In this present case, we describe an interesting family history which included three generations. A couple, married for 4 years, was referred to the genetic clinic due to infertility and family chromosome anomalies. A GTG-band chromosome analysis indicated that the male partner's karyotype was 45, XY, t(3; 18)(q11; ptel)t(13; 14)(q10; q10). The same double balanced translocation was found in two others family members.