DOUBLE TRANSLOCATION: AN INTERESTING FAMILY HISTORY

UYSAL A. O., ULUDAĞ A., SILAN F., Ercelen N., Zafer C., ÖZDEMİR Ö.

BALKAN JOURNAL OF MEDICAL GENETICS, cilt.16, sa.1, ss.77-80, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.2478/bjmg-2013-0022
  • Dergi Adı: BALKAN JOURNAL OF MEDICAL GENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.77-80
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Double balanced translocations are particularly rare and the risk of a fetus with an unbalanced chromosomal anomaly is greater than for single translocation carriers. In this present case, we describe an interesting family history which included three generations. A couple, married for 4 years, was referred to the genetic clinic due to infertility and family chromosome anomalies. A GTG-band chromosome analysis indicated that the male partner's karyotype was 45, XY, t(3; 18)(q11; ptel)t(13; 14)(q10; q10). The same double balanced translocation was found in two others family members.