DOUBLE TRANSLOCATION: AN INTERESTING FAMILY HISTORY


UYSAL A. O. , ULUDAĞ A. , SILAN F. , Ercelen N., Zafer C., ÖZDEMİR Ö.

BALKAN JOURNAL OF MEDICAL GENETICS, cilt.16, ss.77-80, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 16 Konu: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.2478/bjmg-2013-0022
  • Dergi Adı: BALKAN JOURNAL OF MEDICAL GENETICS
  • Sayfa Sayıları: ss.77-80

Özet

Double balanced translocations are particularly rare and the risk of a fetus with an unbalanced chromosomal anomaly is greater than for single translocation carriers. In this present case, we describe an interesting family history which included three generations. A couple, married for 4 years, was referred to the genetic clinic due to infertility and family chromosome anomalies. A GTG-band chromosome analysis indicated that the male partner's karyotype was 45, XY, t(3; 18)(q11; ptel)t(13; 14)(q10; q10). The same double balanced translocation was found in two others family members.