Biosensing strategies for determination of adenosine-5′-triphosphate


Çatoğlu F., SEZGİNTÜRK M. K.

Biosensors and Bioelectronics: X, vol.29, 2026 (Scopus) identifier

  • Publication Type: Article / Review
  • Volume: 29
  • Publication Date: 2026
  • Doi Number: 10.1016/j.biosx.2026.100751
  • Journal Name: Biosensors and Bioelectronics: X
  • Journal Indexes: Scopus, Chemical Abstracts Core, Chimica, Compendex, EMBASE, MEDLINE, Directory of Open Access Journals
  • Keywords: ATP determination, Biosensors, Electrochemical methods, Optical methods
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Adenosine-5′-triphosphate (ATP) is a fundamental biomolecule that supplies the energy required for virtually all biochemical reactions in living organisms and thus underpins the continuity of life. Rapid and accurate quantification of ATP is critically important in diverse fields such as biomedical research, food safety and clinical diagnostics. Recent advances in biosensor technologies have led to substantial progress in ATP determination methodologies. The use of biological recognition elements including aptamers, antibodies and enzymes in combination with optical or electrochemical transducers has enabled the development of modern biosensors offering high selectivity, enhanced sensitivity, low cost and real-time analysis capabilities. This review provides a comprehensive overview of ATP biosensors, outlining their classification, performance parameters, advantages and limitations, and highlighting emerging trends and future directions in this area.