Fraser Syndrome: A Report of Two Cases

KILINÇ N., Demir S., Demir B.

HASEKI TIP BULTENI-MEDICAL BULLETIN OF HASEKI, vol.53, no.3, pp.273-276, 2015 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.4274/haseki.2503
  • Journal Name: HASEKI TIP BULTENI-MEDICAL BULLETIN OF HASEKI
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.273-276
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Fraser syndrome (cryptophthalmos syndactyly syndrome) is a rare autosomal recessive disorder. The main features are cryptophthalmos (hidden eye), ear, nose and skeletal malformations, syndactyly, laryngeal stenosis and malformation of the uro-genital system, lungs, liver, and the central nervous system. Renal anomalies (unilateral/bilateral agenesis) occur in 85% of cases. These anomalies were first documented by Fraser in 1962. In this paper, we present two cases of Fraser syndrome diagnosed after a normal spontaneous vaginal delivery without prenatal follow-up in the light of the literature.