Detection of deletions and/or amplifications of genes related with lung cancer by multiplex ligation-dependent probe amplification (MLPA) technique

Tepeli E., Muslumanoglu M. H., Uludag A., BUYUKPINARBASILI N., Ozdemir M., Oznur M., ...More

CANCER BIOLOGY & THERAPY, vol.8, no.22, pp.2160-2164, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 22
  • Publication Date: 2009
  • Doi Number: 10.4161/cbt.8.22.9840
  • Journal Name: CANCER BIOLOGY & THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2160-2164
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Background: Lung cancer has the leading mortality rate among all cancers and it is the second most common cause of death following cardiovascular diseases. The aim of the study was determining deleted and/or amplified regions of 64 different loci previously associated with lung cancer, by using Multiplex Ligation-dependent Probe Amplification (MLPA).