SOCIAL ISOLATION STRESS REDUCES HIPPOCAMPAL LONG-TERM POTENTIATION: EFFECT OF ANIMAL STRAIN AND INVOLVEMENT OF GLUCOCORTICOID RECEPTORS

Kamal, A.; Ramakers, G.; Altinbilek, BENGİ; Kas, M.

doi:10.1016/j.neuroscience.2013.10.016

SOCIAL ISOLATION STRESS REDUCES HIPPOCAMPAL LONG-TERM POTENTIATION: EFFECT OF ANIMAL STRAIN AND INVOLVEMENT OF GLUCOCORTICOID RECEPTORS

Kamal A., Ramakers G. M. J., Altinbilek B., Kas M. J. H.

NEUROSCIENCE, cilt.256, ss.262-270, 2014 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 256
Basım Tarihi: 2014
Doi Numarası: 10.1016/j.neuroscience.2013.10.016
Dergi Adı: NEUROSCIENCE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.262-270
Anahtar Kelimeler: depression, cognitive deficits, activity-dependent synaptic plasticity, SYNAPTIC PLASTICITY, BEHAVIORAL STRESS, PLASMA-CORTICOSTERONE, MEMORY, LTP, CA1, DEPRESSION, INDUCTION, MICE, MODULATION
Çanakkale Onsekiz Mart Üniversitesi Adresli: Hayır

Özet

Background: Depressive patients show cognitive impairments that are strongly associated with cortisol levels and hippocampus functioning that interact via unknown mechanisms. In addition, a relation between depression and hippocampal synaptic plasticity was described.