SOCIAL ISOLATION STRESS REDUCES HIPPOCAMPAL LONG-TERM POTENTIATION: EFFECT OF ANIMAL STRAIN AND INVOLVEMENT OF GLUCOCORTICOID RECEPTORS

Kamal A., Ramakers G. M. J., Altinbilek B., Kas M. J. H.

NEUROSCIENCE, cilt.256, ss.262-270, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 256
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.neuroscience.2013.10.016
  • Dergi Adı: NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.262-270
  • Anahtar Kelimeler: depression, cognitive deficits, activity-dependent synaptic plasticity, SYNAPTIC PLASTICITY, BEHAVIORAL STRESS, PLASMA-CORTICOSTERONE, MEMORY, LTP, CA1, DEPRESSION, INDUCTION, MICE, MODULATION
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Hayır

Özet

Background: Depressive patients show cognitive impairments that are strongly associated with cortisol levels and hippocampus functioning that interact via unknown mechanisms. In addition, a relation between depression and hippocampal synaptic plasticity was described.