Akademik Veri Yönetim Sistemi
Sinop Üniversitesi Fen Bilimleri Dergisi, cilt.9, sa.1, ss.184-193, 2024 (Hakemli Dergi)
In this study, the antibacterial and antifungal activity of Abies nordmanniana subsp. equi-trojani cone spangles, which are endemic and endangered and grow in Çanakkale Ida Mountains, was investigated by agar well diffusion and microplate methods. The antibacterial and antifungal activity of distilled water, ethanol, methanol and dimethylsulfoxide (DMSO) extracts of cone spangles was evaluated against gram-positive and gram-negative bacteria and yeasts. As a result, it was determined that the DMSO extract had antibacterial and antifungal activity against the tested microorganisms, while the extract prepared with distilled water had no activity. The antimicrobial activity of the methanol and ethanol extracts varied depending on the microorganism type. When the results of this study were compared with the positive control (penicillin G and fluconazole), it was determined that the extracts were not as effective as the antibiotic and antifungal disc. As a result, it is important to use alternative products that are abundant in nature instead of products derived from endangered species.