Aim: Evaluation of the results of open heart surgery in a newly established cardiovascular clinic: Ankara Numune Education and Research Hospital. Material and Method: Between June 2012 and January 2014, 300 open heart surgeries were performed. Urgent operation was performed in 22 patients (7.3%) because of ST-elevation myocardial infarction and in 1 patient because of left ventricular aneurysm rupture. Coronary artery bypass grafting was performed in 211 (70.3%) patients. The other patients underwent various complex operations such as valve repair, Tirone-David procedure and repair of atrioventricular canal defect. Results: In 3 patients (1%) hospital mortality was seen. Reoperation was performed in 8 patients (2.6%) because of pericardial tamponade and in 9 patients (3%) because of bleeding. Atrial fibrillation was developed in 28 patients (9.3%) in the postoperative period and normal sinus rhythm was established with medical cardioversion. Intraaortic balloon pump(IABP) was used in 4 patients preoperatively and in 11 patients postoperatively, including 15 patients(%5). Discussion: In the current era, the patients who are consulted to cardiovascular surgery clinics become more chronic, high risk and patients with additional co-morbid diseases because of the developments in interventional cardiology. Our newly established center aims to be a nationally and internationally successful clinic which was proved by low mortality and morbidity rates with a team who follows the developments and constantly educate and trained.