Suzuki coupling reactions of 2,4,6-trialkoxyphenylboronic acids with enol triflates: asymmetric synthesis of a lactone template for calyxin assemblage

Cakir S. , MEAD K.

TETRAHEDRON LETTERS, vol.47, no.14, pp.2451-2454, 2006 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 14
  • Publication Date: 2006
  • Doi Number: 10.1016/j.tetlet.2006.01.159
  • Title of Journal : TETRAHEDRON LETTERS
  • Page Numbers: pp.2451-2454


Suzuki coupling reactions between 2,4,6-trialkoxyphenylboronic acids and enol triflates have been found to occur in excellent yield, while the use of an enol tosylate failed to give any of the desired product. This coupling reaction has led to the synthesis of a lactone which could serve as a precursor to several calyxin analogues. (c) 2006 Elsevier Ltd. All rights reserved.