Objectives To reveal the possible relationship between greater tuberosity volume with rotator cuff tendon injuries. Materials and methods In our study, the morphology of the greater tuberosity was evaluated retrospectively by using radiographs and MR images of 335 cases. While critical shoulder angle (CSA) was measured on radiographs, greater tuberosity (GT) area and volume were calculated, and also supraspinatus, infraspinatus, and teres minor tendons were evaluated, on MR images. The relationship of the measurements with the tendon injuries was analyzed statistically. Results Among 188 female and 147 male patients, no statistically significant relationship was found between tendon injuries in terms of gender. The relationships between supra and infraspinatus tendon injuries and GT angle, area, and volume measurements were statistically significant. There was a statistically significant relationship between teres minor injury and GT angle, but no significant correlation with GT area and volume. Finally, there was no statistically significant correlation between all three tendon pathologies and CSA. Conclusion Area, and especially volume measurements, which are morphological features of the GT, may reflect tendon damage without significant degenerative changes in the bone structure. In examinations before tendon damage progresses, GT volume is a morphological feature that needs to be evaluated and may facilitate early recognition of tendinopathies and be an early marker of rotator cuff injuries.