The importance of hemosiderin deposition in the infant brain: an autopsy study

Inanir T. N. , Eren F., Akgoz S., Eren B., Cetin S., Gundogmus U. N. , ...More

HIPPOKRATIA, vol.19, no.2, pp.164-171, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 2
  • Publication Date: 2015
  • Journal Name: HIPPOKRATIA
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.164-171


Background/aim: Iron is an essential element involved in many metabolic processes. Presence and accumulation of iron in various body systems can result in different outcomes. Its accumulation in the central nervous system (CNS) cannot be detected routinely by application of hematoxylin-eosin staining. Detection of the presence of hemosiderin in the brain and cerebellum by application of Perls' dye is of importance in cases of infant deaths.