Natural Products and Synthetic Analogs as a Source of Antitumor Drugs

Sharifi-Rad J., Ozleyen A., TÜMER T., Adetunji C. O., El Omari N., Balahbib A., ...More

BIOMOLECULES, vol.9, no.11, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 9 Issue: 11
  • Publication Date: 2019
  • Doi Number: 10.3390/biom9110679
  • Journal Name: BIOMOLECULES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: phytochemical, phytomedicine, anticancer, natural products, CELL-CYCLE ARREST, BREAST-CANCER CELLS, NF-KAPPA-B, LEAF ESSENTIAL OIL, GROWTH IN-VITRO, CHEMICAL-COMPOSITION, ANTIPROLIFERATIVE ACTIVITY, HALICHONDRIN-B, CYTOTOXIC ACTIVITY, COLON-CANCER
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Cancer is a heterogeneous disease and one of the major issues of health concern, especially for the public health system globally. Nature is a source of anticancer drugs with abundant pool of diverse chemicals and pharmacologically active compounds. In recent decade, some natural products and synthetic analogs have been investigated for the cancer treatment. This article presents the utilization of natural products as a source of antitumor drugs.