Prevalence of MEFV gene mutations in a large cohort of patients with suspected familial Mediterranean fever in Central Anatolia


YILDIRIM M. E. , KÜÇÜK KURTULGAN H., ÖZDEMİR Ö., KILIÇGÜN H., Aydemir D. S. , Baser B., ...More

ANNALS OF SAUDI MEDICINE, vol.39, no.6, pp.382-387, 2019 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 6
  • Publication Date: 2019
  • Doi Number: 10.5144/0256-4947.2019.382
  • Journal Name: ANNALS OF SAUDI MEDICINE
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.382-387

Abstract

BACKGROUND: Familial Mediterranean fever (FMF), an autosomal recessive, autoinflammatory disease that is common in Arabs, Jews, Armenians and Turks, is caused by mutations in the MEFV gene, which encodes a protein called pyrin. The disease is characterised by recurrent fever, peritonitis, pleuritis, abdominal pain and arthralgia.