Prevalence of MEFV gene mutations in a large cohort of patients with suspected familial Mediterranean fever in Central Anatolia

YILDIRIM M. E., KÜÇÜK KURTULGAN H., ÖZDEMİR Ö., KILIÇGÜN H., Aydemir D. S., Baser B., ...More

ANNALS OF SAUDI MEDICINE, vol.39, no.6, pp.382-387, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 6
  • Publication Date: 2019
  • Doi Number: 10.5144/0256-4947.2019.382
  • Journal Name: ANNALS OF SAUDI MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.382-387
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

BACKGROUND: Familial Mediterranean fever (FMF), an autosomal recessive, autoinflammatory disease that is common in Arabs, Jews, Armenians and Turks, is caused by mutations in the MEFV gene, which encodes a protein called pyrin. The disease is characterised by recurrent fever, peritonitis, pleuritis, abdominal pain and arthralgia.