Synthesis, structural characterization, and anion interactions of new triazole-linked urea derivative fully substituted cyclotriphosphazene compounds

ÖZAY Ö., Yildirim M., ÖZAY H.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, cilt.192, sa.3, ss.307-315, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 192 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/10426507.2016.1237950
  • Dergi Adı: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.307-315
  • Anahtar Kelimeler: Azide-alkyne cycloaddition, cyclotriphosphazene, urea, "click" reaction, hexapodal compound, DNA INTERACTIONS, PHOSPHAZENE, IONS, CHEMOSENSOR, SELECTIVITY, THIOUREA, BINDING, DESIGN, POTENT, SENSOR
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Three novel fully substituted urea derivative cyclotriphosphazene compounds 5-7 were synthesized by alkyne-azide 1,3-dipolar cycloaddition reaction of propargyl substituted ureas 2-4 with hexaazide substituted cyclotriphosphazene 1 in the presence of Cu(I) catalyst. All compounds were characterized with spectroscopic techniques such as FT-IR, H-1, C-13, and P-31 nuclear magnetic resonance and mass spectroscopy. Also, the usefulness of compounds 5-7 as anion carriers was investigated by H-1 NMR spectroscopy. For this purpose, H-1 NMR spectra of compounds 5-7 were recorded in the presence of tetrabutylammonium fluoride in DMSO-d(6). It was determined, that the urea protons in the compounds interact with fluoride.