Assessment of antibiotic susceptibility of Ureaplasma urealyticum from prostitutes and outpatient clinic patients using the E-test and agar dilution method

Cakan H., Polat E., Kocazeybek B., Ocal P., Cepni I., Aslan M., ...More

CHEMOTHERAPY, vol.49, no.1-2, pp.39-43, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 1-2
  • Publication Date: 2003
  • Doi Number: 10.1159/000069781
  • Journal Name: CHEMOTHERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.39-43
  • Keywords: Ureaplasma urealyticum, antibiotic susceptibility, E-test, agar dilution method, IN-VITRO ACTIVITY, MYCOPLASMA-HOMINIS, PNEUMONIAE, AZITHROMYCIN, ERYTHROMYCIN
  • Çanakkale Onsekiz Mart University Affiliated: No

Abstract

In this study, a total of 647 vaginal discharge samples were examined. Ureaplasma urealyticum growth was seen in 68 samples (10.5%). The antibiotic sensitivity of 30 types of U. urealyticum was determined with the E-test and agar dilution method. With the agar dilution method, all types were sensitive to ciprofloxacin and ofloxacin (MIC 0.94 mug/ml), tetracycline (MIC 0.125 mug/ml) and doxycycline (MIC 0.125 and 0.190 mug/ml). Furthermore, with the agar dilution method, 18 types (60%) were resistant to roxithromycin and 12 (40%) were sensitive (MIC 12 mug/ml); 3 types (10%) were resistant to erythromycin and 27 (90%) were sensitive (MIC 12 mug/ml); 9 types (30%) were resistant to clarithromycin and 21 (70%) were sensitive (MIC 12 mug/ml), and all types were sensitive to azithromycin (MIC 14 mug/ml). Copyright (C) 2003 S. Karger AG, Basel.