The effect of extremely high glucose concentrations on 21 routine chemistry and thyroid Abbott assays: interference study

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Cuhadar S., Koseoglu M., Cinpolat Y., Bugdayci G., Usta M., Semerci T.

BIOCHEMIA MEDICA, cilt.26, sa.1, ss.53-60, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.11613/bm.2016.004
  • Dergi Adı: BIOCHEMIA MEDICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.53-60
  • Anahtar Kelimeler: assay interference, glucose interference, preanalytical phase, creatinine, Jaffe kinetic assay, thyroid function tests, PERITONEAL-DIALYSIS, CREATININE DETERMINATION, CALCIUM
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Hayır

Özet

Introduction: Extremely high glucose concentrations have been shown to interfere with creatinine assays especially with Jaffe method in peritoneal dialysate. Because diabetes is the fastest growing chronic disease in the world, laboratories study with varying glucose concentrations. We investigated whether different levels of glucose spiked in serum interfere with 21 routine chemistry and thyroid assays at glucose concentrations between 17-51 mmol/L.