Ghrelin levels in children with adenoid or chronic tonsil hypertrophies before and after surgery


Koc S., Ozturk K., Buyukbas S., Kocabas V., Ozer B., Kara M.

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, cilt.73, ss.685-687, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 73 Konu: 5
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.ijporl.2009.01.014
  • Dergi Adı: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
  • Sayfa Sayıları: ss.685-687

Özet

Objective: We aimed to evaluate the ghrelin levels in the children with adenoid or tonsil hyperthrophies.

Objective

We aimed to evaluate the ghrelin levels in the children with adenoid or tonsil hyperthrophies.

Methods

The study included 27 children (17 boys and 10 girls). Mean age was 6.9 ± 3.5 years, ranging from 3 to 16. Ghrelin levels in the patients and their weight and height measurements were evaluated before surgery and after 3 months later of the operation.

Results

While 18 (67%) children were operated for adenoid hypertrophy, 9 (33%) children were operated for adenoid and tonsil hypertrophy. It was found that postoperative ghrelin levels were significantly decreased whereas weight and BMI scores were significantly increased (p < 0.01). A weak correlation was observed between preoperative ghrelin and weight (r = −0.29). This negative correlation became more profound at the postoperative 3rd month examination (r = 0.85) (p < 0.01).

Conclusions

The present study showed that the surgical treatment provides positive contributions on the growing of children with adenoid and tonsil hypertrophies. The ghrelin levels were significantly decreased at the postoperative period in the children, and a negative relationship was observed between the ghrelin levels and the weight. These findings suggest that blood ghrelin levels may be useful as a parameter for following the development of the children.