In the process of Turkish Republic being an EU member, wholesomeness of agricultural products is very important at the pesticide residue concept. The reliability of analytical data produced in the pesticide residue laboratory, and validity of method must be checked with documented evidence. Quality Assurance (QA) and Quality Control (QC) principles are very useful tools for the proving correctness of analytical data. Most of the analytical steps must be controlled in QA/QC system. The purpose of the article reported here was to demonstrate the use of radiotracer technique (C-14-pesticide) for some analytical steps such as, the purity/purification of active ingredient, homogenity of sample processing, extraction efficiency (bound residues) cleanup and recovery in QA/QC system.