Exposure to anesthetic gases among operating room personnel and risk of genotoxicity: A systematic review of the human biomonitoring studies


Yilmaz S., Calbayram N.

JOURNAL OF CLINICAL ANESTHESIA, vol.35, pp.326-331, 2016 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 35
  • Publication Date: 2016
  • Doi Number: 10.1016/j.jclinane.2016.08.029
  • Journal Name: JOURNAL OF CLINICAL ANESTHESIA
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.326-331
  • Keywords: Anesthetic gases, Genotoxicity, Operating room personnel, Cancer risk, MASCULINE SEXUAL-BEHAVIOR, ALKALINE COMET ASSAY, NITROUS-OXIDE, DNA-DAMAGE, PERIPHERAL LYMPHOCYTES, OCCUPATIONAL-EXPOSURE, GENETIC-DAMAGE, CHROMOSOME, NURSES

Abstract

Background and objective: Anesthetic gases have been used for a long time. Adverse effects of anesthetic gases to occupationally exposed people have been well documented in the literature. Due to low solubility, these gases are rapidly eliminated from the human body. Nevertheless, neurotoxic, immunosuppressive, hepatotoxic and reproductive toxicological effects have been shown in many of the scientific works. However, there is no detailed systematic bio-monitoring review about genotoxicity risk among occupationally exposed people. We herein performed systematic review based on relevant studies.