Harran Üniversitesi Veteriner Fakültesi Dergisi, vol.10, no.1, pp.36-42, 2021 (Peer-Reviewed Journal)
Coffee is one of the most widely consumed hot beverages in the world. Melanoidins, which are formed with
brown color during coffee roasting, are reported to be a strong antioxidant. Discussions related to the more and less
consumption of coffee still continue. This study investigated the effect of a low and high amount of coffee consumption on
antioxidant parameters in this context. A total of 15 female New Zealand rabbits weighing 1500-2500 g were used in the
study. The control group was fed as ad-libitum control with basal feed. 1% and 5% Turkish coffee were added to the feed of
the 1% TC and 5% TC groups, respectively. Blood was collected once a week throughout the study. All animals were
euthanized in accordance with ethical rules at the end of the study. Samples (plasma and tissue) were taken for the
analyses. Glutathione (GSH) and malondialdehyde (MDA) analyses were performed on all samples. Plasma GSH values were
observed to increase in the groups given TC according to the analyses. Plasma MDA values decreased in the TC groups. An
increase was observed in liver and heart tissue in the TC group upon the evaluation of tissue GSH parameters. MDA values
were found to decrease in lung, heart, and kidney tissues in TC groups. Additional effects were observed in plasma and
tissues in the 5% TC group upon the evaluation of 1% TC and 5% TC groups. No statistical differences were found in
performance parameters. It has been revealed as a result that TC is a strong antioxidant, and its effect increases in high
consumption.