Membranoproliferative glomerulonephritis in a patient with Wilson's disease

ÖZÇAKAR Z. B., Ekim M., ENSARİ A., KULOĞLU Z., YÜKSEL S., Acar B., ...More

Journal of Nephrology, vol.19, no.6, pp.831-833, 2006 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 6
  • Publication Date: 2006
  • Journal Name: Journal of Nephrology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.831-833
  • Keywords: Children, D-Penicillamine, Membranoproliferative glomerulonephritis, Wilson's disease
  • Çanakkale Onsekiz Mart University Affiliated: No


Wilson's disease is an autosomal recessive disorder of hepatobiliary copper metabolism. Glomerular diseases can ensue during the course of Wilson's disease and membranous nephropathy is the eventual pathology in the majority of these cases. Membranoproliferative glomerulonephritis (MPGN) has rarely been reported in patients with Wilson's disease. Further, in this report, we present a patient with Wilson's disease who had developed MPGN during follow-up due to D-penicillamine therapy. This case is presented to draw attention to the rare association of Wilson's disease and MPGN and to discuss the possible underlying causes.