Traffic-Related Air Pollution, Blood Pressure, and Adaptive Response of Mitochondrial Abundance

Zhong J., Cayir A., Trevisi L., Sanchez-Guerra M., Lin X., Peng C., ...More

CIRCULATION, vol.133, no.4, pp.378-387, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 133 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.1161/circulationaha.115.018802
  • Journal Name: CIRCULATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.378-387
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Background Exposure to black carbon (BC), a tracer of vehicular-traffic pollution, is associated with increased blood pressure (BP). Identifying biological factors that attenuate BC effects on BP can inform prevention. We evaluated the role of mitochondrial abundance, an adaptive mechanism compensating for cellular-redox imbalance, in the BC-BP relationship.