Akademik Veri Yönetim Sistemi
Turkish Journal of Analytical Chemistry (Online), cilt.7, sa.3, ss.257-267, 2025 (Hakemli Dergi)
The aim of this study was to simultaneously quantify 11 metal(oid)s in
fingernails by inductively coupled plasma-mass spectrometry (ICP-MS) and
to demonstrate the intra-day reproducibility and time-dependent
variability of the measurements. Fingernail samples without nail polish
were taken from the female subject in the research team twice in 2020
and three times in 2023. The nails of both hands were combined in a nail
pool. Each nail pool was considered as one sample (n= 5).
Simultaneous determination of Cr, Cu, Zn, As, Se, Sr, Cd, Sb, Hg, Tl,
and Pb was carried out with 3 consecutive intra-day readings. The ages
of the samples were 1150 and 939 days (aged) and 9, 14, and 41 days
(current samples), respectively. The mean relative standard deviation
(RSD) of 3 consecutive intraday measurements was 5.26%, and Kendall's W
value was 0.99. Kruskall-Wallis test showed no significant difference
between the three measurements (p<.05). Spearman rho values and
p-values of repeated measurements in 3 years period were found to be
52Cr (rs=0.884, p=0.000), 63Cu (rs= -0.862, p= 0.000), 66Zn (rs= -0.436,
p= 0.104), 75As (rs= -0.840, p= 0.000), 78Se (rs= 0.524, p= 0.045),
88Sr (rs= 0.022, p= 0.938), 111Cd (rs= 0.273, p= 0.325); 121Sb (rs=
0.822, p= 0.000), 201Hg (rs= 0.316, p= 0.251), 205Tl (rs= 0.165, p=
0.557) and 208Pb (rs= 0.197, p= 0.483), respectively. Intraday
measurements of fingernail samples by ICP-MS showed high reproducibility
and analytical precision. It was determined that time-dependent changes
in element concentrations were not linear, and the elements showed
different correlations.