Electroanalysis, cilt.38, sa.2, 2026 (SCI-Expanded, Scopus)
Curcumin, a bioactive polyphenolic compound derived from Curcuma longa, has attracted increasing attention due to its potent antioxidant, anticancer, and anti-inflammatory properties. Accurate quantification of curcumin in complex matrices such as food, biological fluids, and pharmaceuticals is crucial for quality control and therapeutic monitoring. Electrochemical sensing has recently emerged as a promising analytical approach owing to its simplicity, rapid response, and potential for on-site analysis. The incorporation of nanomaterials into electrode architectures has significantly improved sensor performance by enhancing electron transfer kinetics, catalytic activity, and surface area. This review summarizes the recent advances in electrochemical detection of curcumin with a focus on nanomaterial-based electrode modifications, including metal nanoparticles, carbon nanostructures, and conducting polymers. Comparative insights into sensor fabrication strategies, detection mechanisms, and analytical parameters are discussed. Furthermore, current challenges related to reproducibility, selectivity, and real-sample analysis are highlighted, along with future perspectives for the development of miniaturized and robust curcumin biosensors.