Responsive tunable colloidal soft materials based on p(4-VP) for potential biomedical and environmental applications


ŞAHİNER N. , ÖZAY Ö.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, cilt.378, ss.50-59, 2011 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 378
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.colsurfa.2011.01.053
  • Dergi Adı: COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
  • Sayfa Sayıları: ss.50-59

Özet

Tunable poly(4-vinylpyridine) (p(4-VP)) nanoparticles were synthesized in an oil-in-water emulsion using ethylene glycol dimethacrylate (EGDMA) as the cross-linker and ammonium persulfate (APS) as the initiator. The modification of p(4-VP) particles with N-alkyl quaternization was carried out through reacting with various quaternization agents containing carbon chains of various lengths, such as HCl, bromoethane, 1-bromobutane and 1-bromohexane. The obtained nanostructures were demonstrated to be resourceful materials as they are adaptable in terms of charge, size, hydrophilic/hydrophobic nature and magnetic responsive ability, rendered by encasing magnetic ferrites in the particles, for guidable use. Furthermore, the p(4-VP) particles have been shown to be inventive materials for biomedical applications, such as drug release systems using a model drug release of Naproxene Sodium, and as environmental materials to remove organic toxic phenols. (C) 2011 Elsevier B.V. All rights reserved.

Tunable poly(4-vinylpyridine) (p(4-VP)) nanoparticles were synthesized in an oil-in-water emulsion using ethylene glycol dimethacrylate (EGDMA) as the cross-linker and ammonium persulfate (APS) as the initiator. The modification of p(4-VP) particles with N-alkyl quaternization was carried out through reacting with various quaternization agents containing carbon chains of various lengths, such as HCl, bromoethane, 1-bromobutane and 1-bromohexane. The obtained nanostructures were demonstrated to be resourceful materials as they are adaptable in terms of charge, size, hydrophilic/hydrophobic nature and magnetic responsive ability, rendered by encasing magnetic ferrites in the particles, for guidable use. Furthermore, the p(4-VP) particles have been shown to be inventive materials for biomedical applications, such as drug release systems using a model drug release of Naproxene Sodium, and as environmental materials to remove organic toxic phenols.