Characterization and use of (E)-2-[(6-methoxybenzo[d]thiazol-2-ylimino)methyl]phenol as an anion sensor and a DNA-binding agent

Barare B., YILDIZ M., Unver H., Aslan K.

TETRAHEDRON LETTERS, vol.57, no.5, pp.537-542, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.1016/j.tetlet.2015.12.071
  • Journal Name: TETRAHEDRON LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.537-542
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

We report the spectroscopic characterization, DNA binding, and anion sensor properties, of a Schiff base, that is, (E)-2-[(6-methoxybenzo[d]thiazol-2-ylimino)methyl]phenol from the reaction of 2-hydroxyben-zaldehyde with 2-amino-6-methoxybenzothiazole. Colorimetric measurements revealed that the title compound was sensitive to F-, AcO-, CN-, and OH- anions. Fluorescence measurements demonstrated that the title compound can be used to detect CN-. The interactions between the receptor and anions were confirmed using H-1 NMR titration method. The UV-Vis spectroscopy studies of the interactions between the compound and calf thymus DNA (CT-DNA) revealed intercalative binding of CT-DNA to the title compound. (C) 2015 Elsevier Ltd. All rights reserved.