The protective effects of dexmedetomidine against apoptosis in retinal ischemia/reperfusion injury in rats

Gencer B., Karaca T., Tufan H. A., Kara S., ARIKAN S., Toman H., ...Daha Fazla

CUTANEOUS AND OCULAR TOXICOLOGY, cilt.33, sa.4, ss.283-288, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3109/15569527.2013.857677
  • Dergi Adı: CUTANEOUS AND OCULAR TOXICOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.283-288
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Objective: Dexmedetomidine is an alpha 2 adrenoceptor agonist and can be used for postoperative sedation, analgesia and anesthesia-sparing properties. Furthermore, the neuroprotective effects against ischemia/reperfusion (I/R) injury in the central nervous system have been shown in experimental studies. This study aimed to investigate the protective effects of dexmedetomidine against apoptosis in retinal I/R injury in the rat.