Akademik Veri Yönetim Sistemi
3rd International Health Services Congress, Mersin, Türkiye, 3 - 04 Şubat 2026, cilt.1, sa.1, ss.182-183, (Özet Bildiri)
Klebsiella pneumoniae, a Gram-negative bacterial species belonging to the Enterobacteriaceae family, is a capsule-forming and facultatively anaerobic bacterium. This bacterium can be found in various environments, including hospitals and the human body. In the human body, it is particularly abundant in areas such as the gastrointestinal tract, throat, and skin. In individuals with weakened immune systems, it acts as an opportunistic pathogen, causing various infectious diseases, including urinary tract infections, pneumonia, and wound infections. Treatment of these infections is quite difficult due to this bacterium's multidrug resistance to antibiotics. Therefore, alternative and innovative treatment approaches are currently being sought. In this study, the antibacterial activity of 20 different commercial fixed and essential oils against Klebsiella pneumoniae was investigated using the agar well diffusion method. The tested almond oil, oud oil, grapeseed oil, peanut oil, seaweed oil, narcissus flower oil, chamomile oil, pine turpentine oil, black cumin oil, bay leaf seed oil, rose oil, coconut oil, nettle oil, St. John's wort oil, and olive oil were determined to have no antibacterial activity. In contrast, vanilla oil formed an inhibition zone of 13.96 ± 0.21 mm, jasmine oil 10.72 ± 0.33 mm, ginger oil 30.98 ± 3.01 mm, black pepper oil 13.69 ± 1.03 mm, and lavender oil 13.42 ± 2.81 mm. Although the antibacterial activity of some plant oils was not detected in this study, numerous studies in literature report their antimicrobial activity. The presence of biologically active components in the oils' chemical composition is very important for antibacterial activity. Therefore, the inability to detect antibacterial activity may be due to the low or absent levels of biologically active components in the oils' chemical composition. However, the presence of antibacterial activity in vanilla, ginger, jasmine, black pepper, and lavender oils suggests that these oils could serve as alternatives to antibiotics. In conclusion, this indicates that some plant oils may be an alternative treatment for multidrug-resistant bacteria; therefore, more detailed studies are needed.
Keywords: Essential oil, Fixed oil, Antibacterial activity