Situs inversus totalis and schizophrenia comorbidity

Kaymak S. U., Şahin E. K., Uğurlu G. K., Ünal Ö., ATAGÜN M. İ., CAN S. S., ...More

Turk Psikiyatri Dergisi, vol.28, no.4, 2017 (SSCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.5080/u20549
  • Journal Name: Turk Psikiyatri Dergisi
  • Journal Indexes: Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
  • Keywords: Schizophrenia, Situs inversus, Tetralogy of fallot
  • Çanakkale Onsekiz Mart University Affiliated: No

Abstract

The comorbidity of structural or genetic diseases with schizophrenia is seen as an opportunity to understand the formation of schizophrenia. This case report presents a patient with comorbidity of schizophrenia, tetralogy of fallot (TOF) and total situs inversus. TOF is a cyanotic heart disease, which can be linked to 22q11 deletion and trisomy 21. Situs inversus totalis (SIT) is a congenital condition in which the major visceral organs, including the heart, are positioned in a mirror image from normal conditions. The comorbidity of TOF and SIT is quite rare. In our case report, schizophrenia is added to this rare comorbidity. This case report discussed the comorbidity and probable causal relationships. Furthermore, the research method of how transposition in internal organs is reflected in brain lateralization is also presented.