Selenium or ozone: Effects on liver injury caused by experimental iron overload


Guevendi G. F. , EROĞLU H. A. , MAKAV M., Guvendi B., Adalre Y.

LIFE SCIENCES, vol.262, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 262
  • Publication Date: 2020
  • Doi Number: 10.1016/j.lfs.2020.118558
  • Title of Journal : LIFE SCIENCES

Abstract

Aims: Iron is an important metal ion as a biocatalyst on the other hand iron overload causes various diseases. Iron overload can result in fibrosis and hepatocellular carcinoma with various pathophysiological mechanisms, including oxidative damage in the liver. Therefore; in this study the effects of ozone and selenium-whose antioxidant properties are known- were evaluated in liver injury induced by iron overload.