Effectiveness of Brain Protection With Histidine-Tryptophan-Ketoglutarate Solutions


OĞUZ S., AŞGÜN H. F. , Buyuk B.

HEART SURGERY FORUM, vol.23, no.4, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.1532/hsf.3103
  • Journal Name: HEART SURGERY FORUM
  • Journal Indexes: Science Citation Index Expanded, Scopus, EMBASE, MEDLINE

Abstract

Background: Tissue-protective solutions increase resistance of cells to ischemic conditions. Especially in carotid and aortic arch surgeries where the brain perfusion is at risk, these solutions may be beneficial to prevent ischemic brain damage. This study was designed to demonstrate the effectiveness of histidine-tryptophan-ketoglutarate (HTK) solution in increasing resistance of brain tissue to ischemic conditions.