Effectiveness of Brain Protection With Histidine-Tryptophan-Ketoglutarate Solutions

OĞUZ S. , AŞGÜN H. F. , Buyuk B.

HEART SURGERY FORUM, vol.23, no.4, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.1532/hsf.3103
  • Title of Journal : HEART SURGERY FORUM


Background: Tissue-protective solutions increase resistance of cells to ischemic conditions. Especially in carotid and aortic arch surgeries where the brain perfusion is at risk, these solutions may be beneficial to prevent ischemic brain damage. This study was designed to demonstrate the effectiveness of histidine-tryptophan-ketoglutarate (HTK) solution in increasing resistance of brain tissue to ischemic conditions.