MEDICINAL CHEMISTRY, vol.14, no.5, pp.495-507, 2018 (Journal Indexed in SCI)
Article / Article
Title of Journal :
Ssap-NtrB, cancer therapy, cell cytotoxicity, prodrugs, quantum chemical parameter, molecular docking, ESCHERICHIA-COLI, BIOACTIVATION, AMISULPRIDE, EXTRACTS, TUMOR
Background: Directed Enzyme Prodrug Therapy (DEPT) as an alternative method against conventional cancer treatments, in which the non-toxic prodrug is converted to highly cytotoxic derivative, has attracted an ample attentions in recent years for cancer therapy studies.