Potassium fluoride/alumina mediated simple synthesis of Hantzsch 1,4-dihydropyridines


AYDIN F. , Özen R.

JOURNAL OF CHEMICAL RESEARCH, no.7, pp.486-487, 2004 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: Issue: 7
  • Publication Date: 2004
  • Doi Number: 10.3184/0308234042037284
  • Title of Journal : JOURNAL OF CHEMICAL RESEARCH
  • Page Numbers: pp.486-487

Abstract

A general and practical technique to achieve synthesis of 1,4-dihydropyridines in excellent yields has been investigated using potassium fluoride/alumina (KF/Al2O3) as a solid base. The ammonia was obtained either from thermal decomposition of ammonium acetate or by passing ammonia gases in the form of bubbled through hetereogenous reaction medium using an apparatus.