Intrarenal reflux İntrarenal reflü

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Yılmaz N., YÜKSEL S.

Pamukkale Medical Journal, vol.12, no.2, pp.347-350, 2019 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.31362/patd.524048
  • Journal Name: Pamukkale Medical Journal
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.347-350
  • Keywords: prophylaxis, renal papilla, scar, Vesico-ureteral reflux
  • Çanakkale Onsekiz Mart University Affiliated: No


Vesicoureteral reflux (VUR) is called a condition in which urine flows backward from the bladder to the kidneys via ureters. Intrarenal reflux (IRR) is defined as the urine back flow from the renal pelvis into the collecting ducts (pyelo-tubular backflow). IRR is usually associated with high-grade VUR. In this case report, a male infant with high-grade VUR associated with IRR was presented. During the 2-year follow-up, he did not use antibiotic prophylaxis, and his IRR improved spontaneously and VUR regressed. Incidence of IRR in patients with VUR is reported between 2% and 10%. Since the high-grade VUR is known to spontaneously recover, it is recommended that high degree VUR associated IRR should be followed with low-dose antibiotic prophylaxis. Because, even if there is an IRR, many studies are reported that the prognosis cannot be affected, if there is no febrile urinary tract infection. The patient could not use antibiotic prophylaxis, and urinary tract infections occurred two times during the follow-up period. However, IRR was disappeared, and the degree of VUR decreased significantly. The risk of scarring in the kidney increases with the presence of IRR. Therefore, the presence of IRR should be evaluated more carefully in infants and neonates with high-grade VUR.