The aim of this study was to reveal the relationships between nutritional parameters and pulmonary functions in patients with chronic obstructive pulmonary disease (COPD) in both sexes. Spirometric, laboratory, and demographic data of 450 consecutive patients were analysed retrospectively. Mates had significantly greater pack-years of smoking, more severe airway obstruction, and lower body mass index (BMI). In non-smokers, BMI was significantly lower in men independent of age and pulmonary functions. Creatine kinase levels showed no correlation with any pulmonary function parameters. Serum albumin levels correlated better than BMI with pulmonary functions. In conclusion, females with COPD were maintained weight better than men.